Platinum derivatives used as chemotherapeutic drugs such as cisplatin and oxaliplatin have a potent antitumor activity.However, severe side effects such as nephro-, oto-, and neurotoxicity are associated with their use.Effects Posters and side effects of platinum-based drugs are in part caused by their transporter-mediated uptake in target and non
Lactic acid bacteria have been considered to be a very important species during sourdough fermentation.In order to explore the effects of bifidobacteria fermentation on thermal, physico-chemical and structural properties of wheat starch during dough fermentation, starch granules were separated from the fermented dough at different fermentation time
Human pumping-accessories languages are rule governed, but almost invariably these rules have exceptions in the form of irregularities.Since rules in language are efficient and productive, the persistence of irregularity is an anomaly.How does irregularity linger in the face of internal (endogenous) and external (exogenous) pressures to conform to
Urinary incontinence (UI) is the involuntary leakage of urine, while overactive bladder (OAB) is characterised by frequency, nocturia and urgency, with or without incontinence.This paper provides guidelines for the management of UI and OAB, focusing on primary health care.Although UI and OAB negatively impact on the patients quality of life more se
Following a synthesis of published archaeological investigations in the territory of Sezze by the team of the University of Groningen within the Pontine Region Project (PRP), this paper discusses the methodology and first results of two more recent fieldwork projects within the framework of the PRP, both funded by the Netherlands Organisation for S